A total of 292 patients completed the survey (response rate = 94%); 12.3% of patients were active marijuana users, 39.0% were past users, and 48.6% were never users. Among current and past users, 16.4% of patients used marijuana for disease symptoms, the majority of whom felt marijuana was “very helpful” for relief of abdominal pain, nausea, and diarrhea.
Half of the never users expressed an interest in using marijuana for abdominal pain, were it legally available (Allegretti, Jessica, Andrew Courtwright, and colleagues).
Cannabinoid Receptor-2 Ameliorates Inflammation in Murine Model of Crohn’s Disease.
Cannabinoid receptor stimulation may have positive symptomatic effects on inflammatory bowel disease [IBD] patients through analgesic and anti-inflammatory effects. The cannabinoid 2 receptor [CB2R] is expressed primarily on immune cells, including CD4+ T cells, and is induced by active inflammation in both humans and mice. We therefore investigated the effect of targeting CB2R in a preclinical IBD model. Continue to Study